Nausea Drugs Linked To Heightened Risk Of Stroke

Nausea Drugs Linked To Heightened Risk Of Stroke

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Drugs known as antidopaminergic antiemetics (ADAs) that are widely used to relieve nausea and vomiting caused, for instance, by migraine, chemotherapy or radiotherapy, and after surgery are associated with an increased risk of ischaemic stroke, finds a study published by The BMJ today.

The results show that all three ADAs studied (domperidone, metopimazine, and metoclopramide) were associated with an increased risk, especially in the first days of use, but the highest increase was found for metopimazine and metoclopramide. The researchers suggest that the potential action of ADAs on blood flow to the brain could explain this higher risk.

Like antipsychotics, ADAs are antidopaminergic drugs—they work by blocking dopamine activity in the brain. Antipsychotics have been associated with an increased risk of ischaemic stroke, but whether this risk could extend to other antidopaminergics including ADAs is not known.


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Tammy Cuthbert Garcia

Tammy Cuthbert Garcia

Tammy Cuthbert Garcia is an organic lifestyle entrepreneur, podcast host, radio show personality, health writer and spokesperson for health freedom. She began hosting “Naturally Inspired Podcast” in 2019 where she interviews top minds in lifestyle solutions and health freedom. She makes guest host appearances on AM/FM radio and also has a daily show called “Naturally Inspired Daily”.  

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